GLP-1 Isn’t Just a Prescription. It’s Changing How America Eats

by Sifter
,
Judy Seybold
,
MS, RDN, LD, CLC
December 18, 2025
December 18, 2025
Medications like Ozempic, Wegovy, and Mounjaro are transforming weight management at unprecedented scale—and with it, consumer food behavior. Sifter turns this shift into a win for retailers, CPGs, and consumers alike.
Sifter is the Food as Medicine Platform.

Nearly 1 in 8 U.S. adults report having used a GLP-1 medication for weight loss. Spending on these drugs has surged past $70 billion, making GLP-1s the fastest-growing category in healthcare. But appetite suppression is only part of the story.

GLP-1 users are eating less, eating differently, and seeking foods that:

  • Reduce nausea and GI side effects
  • Protect muscle mass
  • Deliver more nutrition in smaller portions
  • Support long-term success beyond the medication

This shift is creating a new nutrition imperative—and a major opportunity for food brands and retailers who respond intelligently.

Food Is Now a Companion to GLP-1 Therapy

Clinical evidence is clear: what patients eat before, during, and after GLP-1 therapy significantly affects outcomes.

That’s where Sifter changes the game to a positive business impact. We deliver a Food Is Medicine platform that helps retailers and CPGs support GLP-1 users at the exact moment food decisions are made.

Sifter’s GLP-1-specific capabilities include:

  • A proprietary GLP-1 food filter identifying nutrient-dense, clinically aligned
    foods across all grocery categories
  • Exclusion of foods high in added sugars, excess sodium, cholesterol, and saturated fat
  • UPC-level accuracy across 35,000+ national and local retailers
  • Personalized grocery lists tailored to therapy stage, co-existing conditions, preferences, and intolerances
  • In-store barcode scanning that guides decisions in real time

The result: seamless movement from prescription to grocery cart.

Why This Matters for CPGs and Retailers

GLP-1 is not reducing demand for food—it’s reshaping it. This creates a strategic opening to:

  • Identify fast-growing GLP-1-aligned consumer segments
  • Align product innovation and reformulation with clinically relevant nutrition profiles
  • Merchandise, message, and promote foods that support GLP-1 success
  • Become trusted partners in the rapidly expanding Food Is Medicine ecosystem

Through Sifter—and in partnership with Circana’s consumer behavior intelligence—brands and retailers gain both the insight and the execution layer needed to win this shift.

GLP-1 is changing how people eat—permanently. Sifter makes that connection actionable. Let’s talk about how your brand or retail strategy can lead in the GLP-1 era.

Visit www.siftersolutions.com to request a briefing today.

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